Linear Immunoglobulin A Disease

Drug-induced linear immunoglobulin A bullous dermatosis. Reports have shown that as many as two-thirds of occurrences may be drug-induced. Linear immunoglobulin A IgA bullous dermatosis also known as linear IgA disease is an autoimmune mucocutaneous disorder characterized by subepithelial bullae with IgA autoantibodies directed against several different antigens in the basement membrane zone. Drug-induced linear immunoglobulin A disease. Five 71 also suffered from ulcerative colitis the prevalence of ulcerative colitis in the UK. Garel B Ingen-Housz-Oro S Afriat D Prost-Squarcioni C Tétart F Bensaid B Bara Passot C Beylot-Barry M Descamps V Duvert-Lehembre S Grootenboer-Mignot S Jeudy G Soria A Valnet-Rabier MB Barbaud A Caux F Lebrun-Vignes B. In drug-induced LAD certain uncommon and atypical clinical features can occur.

Drug-induced linear immunoglobulin A disease.

8124643 Indexed for MEDLINE Publication Types. Linear immunoglobulin A bullous disease is an autoimmune subepidermal blistering disease that has been described in both children and adults. A French retrospective pharmacovigilance study of 69 cases. The offending drugs include antibiotics predominantly vancomycin nonsteroidal anti-inflammatory agents and diuretics. Linear immunoglobulin A disease LAD is a rare autoimmune vesicular-bullous disease that is either idiopathic or drug-induced most commonly by vancomycin and in rare instances by amlodipine. Deposits of antibodies in the skin cause damage to the structure of the skin and a blister appears.

Linear Immunoglobulin A Iga Disease Dermatologic Disorders Merck Manuals Professional Edition

Linear immunoglobulin a disease. Drug-induced linear immunoglobulin A bullous dermatosis. The condition is called Linear IgA disease because a type of protein called immunoglobulin A IgA can be seen deposited under the outer layer of the. Two real ancestral enemies.

A further three patients with this association from other British centres were also reviewed. Seventy adult patients with linear IgA disease were studied. In drug-induced LAD certain uncommon and atypical clinical features can occur.

Linear immunoglobulin A bullous disease is an autoimmune subepidermal blistering disease that has been described in both children and adults. What is linear IgA bullous disease. 1Department of Dermatology Bristol Royal Infirmary Bristol and Churchill Hospital Oxford United Kingdom.

A similar condition affecting children is known as Chronic Bullous Disease of Childhood CBDC. Five 71 also suffered from ulcerative colitis the prevalence of ulcerative colitis in the UK. The bodys immune system produces antibodies known as Immunoglobulin A IgA which are incorrectly deposited in the top layer of the skin in a line hence the term linear.

In this review we discuss the clinical presentation of and treatment options for linear immunoglobulin A disease dermatitis herpetiformis pemphigus vulgaris pemphigus foliaceus PNP bullous pemphigoid mucus membrane pemphigoid epidermolysis bullosa acquisita and inherited epidermolysis bullosa. Linear immunoglobulin Ig A dermatosis is a rare immune-mediated blistering skin disease that is defined by the presence of homogeneous linear deposits. Reports have shown that as many as two-thirds of occurrences may be drug-induced.

Linear immunoglobulin A IgA bullous dermatosis also known as linear IgA disease is an autoimmune mucocutaneous disorder characterized by subepithelial bullae with IgA autoantibodies directed against several different antigens in the basement membrane zone. Linear immunoglobulin A IgA bullous dermatosis also known as linear IgA disease is an autoimmune mucocutaneous disorder characterized by subepithelial bullae with IgA autoantibodies directed against several different antigens in the basement membrane zone. Drug-induced linear immunoglobulin A disease.

Fortuna G1 Aria M Marasca F Salas-Alanís JC. We report a 39-year-old woman with clinical features of LAD and with circulating IgA and IgG autoantibodies to the 180 kDa bullous pemphigoid antigen BP180.

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We report a 39-year-old woman with clinical features of LAD and with circulating IgA and IgG autoantibodies to the 180 kDa bullous pemphigoid antigen BP180.

Linear immunoglobulin A bullous disease is an autoimmune subepidermal blistering disease that has been described in both children and adults. This disease can often be difficult to treat even with usually effective medications such as rituximab. A similar condition affecting children is known as Chronic Bullous Disease of Childhood CBDC. A further three patients with this association from other British centres were also reviewed. Linear IgA disease is a very rare blistering condition of the skin in adults. In this review we discuss the clinical presentation of and treatment options for linear immunoglobulin A disease dermatitis herpetiformis pemphigus vulgaris pemphigus foliaceus PNP bullous pemphigoid mucus membrane pemphigoid epidermolysis bullosa acquisita and inherited epidermolysis bullosa. Two real ancestral enemies. Fortuna G1 Aria M Marasca F Salas-Alanís JC. 1Department of Dermatology Bristol Royal Infirmary Bristol and Churchill Hospital Oxford United Kingdom.

8124643 Indexed for MEDLINE Publication Types. Linear IgA disease is a very rare blistering condition of the skin in adults. A similar condition affecting children is known as Chronic Bullous Disease of Childhood CBDC. Fortuna G1 Aria M Marasca F Salas-Alanís JC. We report a 39-year-old woman with clinical features of LAD and with circulating IgA and IgG autoantibodies to the 180 kDa bullous pemphigoid antigen BP180. Two real ancestral enemies. 8124643 Indexed for MEDLINE Publication Types.